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The Lasso Lab works at the intersection of computational biology and virology. We apply computational approaches—including structural bioinformatics, network biology, and machine learning—to study sequence-to-structure-to-function relationships in viral and host proteins that drive infection by (re)emerging zoonotic viruses.

With globalization and climate change accelerating viral spillover and outbreak risks, our work aims to establish predictive and therapeutic strategies to mitigate future pandemics. Our research focuses on three key areas:

1. The Zoonotic and Pathogenic Potential of Emerging Viruses
2. Host Genetic Variation in Viral Infections
3. Molecular Interactions Underpinning Viral Infection Diseases

Our laboratory thrives on collaboration, working closely with both experimental and computational groups within the UK and globally to drive multidisciplinary discoveries. Importantly, we are committed to fostering an inclusive, supportive, and intellectually stimulating environment.


Latest news

  • Welcome Charlie!
    Charlie Barnes has joined the lab. Charlie is a 4th-year Medicine student at the University of Brighton, currently intercalating in Mathematics, Computers, and Medicine at UCL.
  • Welcome Jiahe!
    Jiahe Lin has joined the lab. She is in her final year of the MSci in Human Sciences and Evolution at UCL.
  • LassoLab Website is launched
    The LassoLab has officially launched! While the site is still evolving, we’re excited to share our progress — stay tuned for more!